Badania naukowe

W Klinice prowadzone są badania własne, jak i we współpracy z innymi ośrodkami krajowymi i zagranicznymi. Wyposażenie umożliwia wykonywanie szerokiego zakresu analiz klinicznych i biochemicznych. Główne obszary zainteresowań Zespołu to: żywienie, mukowiscydoza i nieswoiste zapalenia jelit.

Partnerzy zagraniczni:

partners

Bibliografia

2016

  • Walkowiak J, Glapa A, Nowak JK, Bober L, Rohovyk N, Wenska-Chyży E, Sobkowiak P, Lisowska A. Pancreatic Elastase-1 Quick Test for rapid assessment of pancreatic status in cystic fibrosis patients. J Cyst Fibros. 2016 Sep;15(5):664-8.
  • Stelmach-Mardas M, Walkowiak J. Dietary Interventions and Changes in Cardio-Metabolic Parameters in Metabolically Healthy Obese Subjects: A Systematic Review with Meta-Analysis. Nutrients. 2016 Jul 28;8(8).
  • Jonczyk-Potoczna K, Nowak JK, Madry E, Katulska K, Stezowska-Kubiak S, Moczko J, Nowicka A, Lisowska A, Walkowiak J. Secretin-enhanced Magnetic Resonance Cholangio-pancreatography in Pancreatic Insufficient and Pancreatic Sufficient Cystic Fibrosis Patients. J Gastrointestin Liver Dis. 2016 Mar;25(1):57-62.
  • Jonczyk-Potoczna K, Nowak JK, Madry E, Katulska K, Stezowska-Kubiak S, Moczko J, Lisowska A, Walkowiak J. Smaller Width of the Pancreatic Duct During Secretin-Enhanced Magnetic Resonance Cholangiopancreatography in Pancreatic-Sufficient Cystic Fibrosis Patients. Pancreas. 2016 Sep;45(8):1175-8.
  • Dziedzic K, Szwengiel A, Górecka D, Gujska E, Kaczkowska J, Drożdżyńska A, Walkowiak J. Effect of Wheat Dietary Fiber Particle Size during Digestion In Vitro on Bile Acid, Faecal Bacteria and Short-Chain Fatty Acid Content. Plant Foods Hum Nutr. 2016 Jun;71(2):151-7.
  • Drzymała-Czyż S, Jończyk-Potoczna K, Lisowska A, Stajgis M, Walkowiak J. Supplementation of ursodeoxycholic acid improves fat digestion and absorption in cystic fibrosis patients with mild liver involvement. Eur J Gastroenterol Hepatol. 2016 Jun;28(6):645-9.
  • Józefczuk J, Mądry E, Nowak J, Walkowiak M, Łochocka K, Banasiewicz T, Pławski A, Kwiecień J, Walkowiak J. Conflicting results of non-invasive methods for detection of Helicobacter pylori infection in children with celiac disease – a preliminary study. Acta Biochim Pol. 2016;63(1):1088.

2015

  • Krzyżanowska P, Pogorzelski A, Skorupa W, Moczko J, Grebowiec P, Walkowiak J. Exogenous and endogenous determinants of vitamin K status in cystic fibrosis. Sci Rep. 2015 Jul 10;5:12000.
  • Lochocka K, Bajerska J, Glapa A, Fidler-Witon E, Nowak JK, Szczapa T, Grebowiec P, Lisowska A, Walkowiak J. Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study. Sci Rep. 2015 Jul 30;5:12015.
  • Nowak JK, Jonczyk-Potoczna K, Adamczak DM, Lisowska A, Walkowiak J. Esophageal pH Monitoring in Children: A Simple Mathematical Formula for pH Probe Positioning. J Pediatr Gastroenterol Nutr. 2015 Aug;61(2):212-4.
  • Nowak JK, Grulkowski I, Karnowski K, Wojtkowski M, Walkowiak J. Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women. Clin Transl Sci. 2015 Dec;8(6):717-21.
  • Nowak JK, Grulkowski I, Karnowski K, Wojtkowski M, Walkowiak J. Optical coherence tomography identifies lower labial salivary gland surface density in cystic fibrosis. PLoS One. 2015 Jan 26;10(1):e0117517.
  • Skrypnik D, Bogdański P, Mądry E, Karolkiewicz J, Ratajczak M, Kryściak J, Pupek-Musialik D, Walkowiak J. Effects of Endurance and Endurance Strength Training on Body Composition and Physical Capacity in Women with Abdominal Obesity. Obes Facts. 2015;8(3):175-87.
  • Lisowska A, Stawińska-Witoszyńska B, Bajerska J, Krzyżanowska P, Walkowiak J. Green tea influences intestinal assimilation of lipids in humans: a pilot study. Eur Rev Med Pharmacol Sci. 2015;19(2):209-14.
  • Drzymala-Czyz S, Stawinska-Witoszynska B, Mądry E, Krzywinska-Wiewiórowska M, Szczepanik M, Walkowiak J, Kwiecien J. Non-invasive detection of Helicobacter pylori in cystic fibrosis–the fecal test vs. the urea breath test. Eur Rev Med Pharmacol Sci. 2014 Aug;18(16):2343-8.
  • Bajerska J, Mildner-Szkudlarz S, Walkowiak J. Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study. J Med Food. 2015 Jun;18(6):698-705.
  • Jozefczuk J, Bancerz B, Walkowiak M, Glapa A, Nowak J, Piescikowska J, Kwiecien J, Walkowiak J. Prevalence of Helicobacter pylori infection in pediatric celiac disease. Eur Rev Med Pharmacol Sci. 2015;19(11):2031-5.

2014

  • Czub E, Nowak JK, Moczko J, Lisowska A, Banaszkiewicz A, Banasiewicz T, Walkowiak J. Comparison of fecal pyruvate kinase isoform M2 and calprotectin in acute diarrhea in hospitalized children. Sci Rep. 4:4769. doi: 10.1038/srep04769.
  • Nowak JK, Grzybowska-Chlebowczyk U, Landowski P, Szaflarska-Poplawska A, Klincewicz B, Adamczak D, Banasiewicz T, Plawski A, Walkowiak J. Prevalence and correlates of vitamin K deficiency in children with inflammatory bowel disease. Sci Rep. 4:4768. doi: 10.1038/srep04768.
  • Grulkowski I, Nowak JK, Karnowski K, Zebryk P, Puszczewicz M, Walkowiak J, Wojtkowski M. Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT. Biomed Opt Express. 5(1): 259–274.
  • Lisowska A, Kobelska-Dubiel N, Jankowska I, Pawłowska J, Moczko J, Walkowiak J. Small intestinal bacterial overgrowth in patients with progressive familial intrahepatic cholestasis. Acta Biochim Pol. 61(1):103-7.
  • Czub E, Nowak JK, Szaflarska-Poplawska A, Grzybowska-Chlebowczyk U, Landowski P, Moczko J, Adamczak D, Mankowski P, Banasiewicz T, Plawski A, Walkowiak J. Comparison of fecal pyruvate kinase isoform M2 and calprotectin in assessment of pediatric inflammatory bowel disease severity and activity. Acta Biochim Pol. 61(1):99-102.
  • Kaluzny L, Szczepanik M, Siwinska-Mrozek Z, Borkowska-Klos M, Cichy W, Walkowiak J. Parenteral nutrition in patients with inborn errors of metabolism – a therapeutic problem. Eur Rev Med Pharmacol Sci. 18(11):1579-82.
  • Stelmach-Mardas M, Mardas M, Walkowiak J, Boeing H. Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges. Proc Nutr Soc. 2014 Nov;73(4):509-18.
  • Stelmach-Mardas M, Mardas M, Warchoł W, Jamka M, Walkowiak J. Successful maintenance of body weight reduction after individualized dietary counseling in obese subjects. Sci Rep. 2014 Oct 14;4:6620.

2013

  • Drzymała-Czyż, S., Kwiecień, J., Pogorzelski, A., Rachel, M., Banasiewicz, T., Pławski, A., Szczawińska-Popłonyk, A., Herzig, K.-H., Walkowiak, J., 2013. Prevalence of Helicobacter pylori infection in patients with cystic fibrosis. J. Cyst. Fibros.
  • Walkowiak J, Cofta S, Mozrzymas R, Siwinska-Mrozek Z, Nowak J, Kaluzny L, Banasiewicz T. Phenylketonuria is not a risk factor for gut mucosa inflammation: a preliminary observation. Eur Rev Med Pharmacol Sci. 17(22):3056-9.
  • Walkowiak J, Bajerska J, Kargulewicz A, Lisowska A, Siedlerski G, Szczapa T, Kobelska-Dubiel N, Grzymisławski M. Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans. Acta Biochim Pol. 60(3):481-3.

2012

  • Banasiewicz, T., Walkowiak, J., Drzymała-Czyż, S., Borejsza-Wysocki, M., Majewski, P., Biczysko, M., Stojcev, Z., Herzig, K.-H., Drews, M., 2012. Stricture of ileo-anal J pouch anastomosis increased the intensity of pouchitis in an experimental rat model. Med. Sci. Monit. 18, BR409–413.
  • Drzymała-Czyż, S., Banasiewicz, T., Tubacka, M., Tarasiuk-Rusek, A., Majewski, P., Drews, M., Walkowiak, J., 2012a. Discrepancy between clinical and histological effects of DHA supplementation in a rat model of pouchitis. Folia Histochem. Cytobiol. 50, 125–129.
  • Drzymała-Czyż, S., Banasiewicz, T., Walas, S., Kościński, T., Wenska-Chyży, E., Drews, M., Walkowiak, J., 2012b. Trace elements and rat pouchitis. Acta Biochim. Pol. 59, 599–601.
  • Krzyżanowska, P., Książyk, J., Kocielińska-Kłos, M., Banaś, E., Kaleta, M., Popińska, K., Szczapa, T., Walkowiak, J., 2012. Vitamin K status in patients with short bowel syndrome. Clin Nutr 31, 1015–1017.
  • Mądry, E., Krasińska, B., Drzymała-Czyż, S., Sands, D., Lisowska, A., Grebowiec, P., Minarowska, A., Oralewska, B., Mańkowski, P., Moczko, J., Walkowiak, J., 2012a. Lactose malabsorption is a risk factor for decreased bone mineral density in pancreatic insufficient cystic fibrosis patients. Eur. J. Hum. Genet. 20, 1092–1095.
  • Mądry, E., Lisowska, A., Grebowiec, P., Walkowiak, J., 2012b. The impact of vegan diet on B-12 status in healthy omnivores: five-year prospective study. Acta Sci Pol Technol Aliment 11, 209–212.
  • Walkowiak, J., Mądry, E., Lisowska, A., Szaflarska-Popławska, A., Grzymisławski, M., Stankowiak-Kulpa, H., Przysławski, J., 2012. Adaptive changes of pancreatic protease secretion to a short-term vegan diet: influence of reduced intake and modification of protein. Br. J. Nutr. 107, 272–276.

2011

  • Bajerska, J., Wozniewicz, M., Jeszka, J., Drzymala-Czyz, S., Walkowiak, J., 2011. Green tea aqueous extract reduces visceral fat and decreases protein availability in rats fed with a high-fat diet. Nutr Res 31, 157–164.
  • Drzymała-Czyż, S., Banasiewicz, T., Tubacka, M., Majewski, P., Biczysko, M., Kościński, T., Drews, M., Walkowiak, J., 2011. Inulin supplementation in rat model of pouchitis. Acta Biochim. Pol. 58, 381–384.
  • Flemström, G., Mäkelä, K., Purhonen, A.K., Sjöblom, M., Jedstedt, G., Walkowiak, J., Herzig, K.H., 2011. Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin. Acta Physiol (Oxf) 201, 141–150.
  • Herzig, K.-H., Purhonen, A.-K., Räsänen, K.M., Idziak, J., Juvonen, P., Phillps, R., Walkowiak, J., 2011. Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus. BMC Geriatr 11, 4.
  • Lisowska, A., Pogorzelski, A., Oracz, G., Siuda, K., Skorupa, W., Rachel, M., Cofta, S., Piorunek, T., Walkowiak, J., 2011a. Oral antibiotic therapy improves fat absorption in cystic fibrosis patients with small intestine bacterial overgrowth. J. Cyst. Fibros. 10, 418–421.
  • Lisowska, A., Pogorzelski, A., Oracz, G., Skorupa, W., Cofta, S., Szydłowski, J., Socha, J., Walkowiak, J., 2011b. Antibiotic therapy and fat digestion and absorption in cystic fibrosis. Acta Biochim. Pol. 58, 345–347.
  • Mądry, E., Fidler, E., Sobczyńska-Tomaszewska, A., Lisowska, A., Krzyżanowska, P., Pogorzelski, A., Minarowski, Ł., Oralewska, B., Mojs, E., Sapiejka, E., Marciniak, R., Sands, D., Korzon-Burakowska, A., Kwiecień, J., Walkowiak, J., 2011. Mild CFTR mutations and genetic predisposition to lactase persistence in cystic fibrosis. Eur. J. Hum. Genet. 19, 748–752.
  • Money, M.E., Walkowiak, J., Virgilio, C., Talley, N.J., 2011. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol 2, 48–56.
  • Stankowiak-Kulpa, H., Krzyżanowska, P., Kozioł, L., Grzymisławski, M., Wanic-Kossowska, M., Moczko, J., Walkowiak, J., 2011. Vitamin K status in peritoneally dialyzed patients with chronic kidney disease. Acta Biochim. Pol. 58, 617–620.

2010

  • Houwen, R.H., van der Doef, H.P., Sermet, I., Munck, A., Hauser, B., Walkowiak, J., Robberecht, E., Colombo, C., Sinaasappel, M., Wilschanski, M., ESPGHAN Cystic Fibrosis Working Group, 2010. Defining DIOS and constipation in cystic fibrosis with a multicentre study on the incidence, characteristics, and treatment of DIOS. J. Pediatr. Gastroenterol. Nutr. 50, 38–42.
  • Krzyzanowska, P., Lisowska, A., Skorupa, W., Pogorzelski, A., Kamińska, B., Cichy, W., Popiel, A., Walkowiak, J., 2010. [Vitamin K deficiency in patients with CF despite supplementation]. Med Wieku Rozwoj 14, 68–72.
  • Lisowska, A., Madry, E., Pogorzelski, A., Szydłowski, J., Radzikowski, A., Walkowiak, J., 2010. Small intestine bacterial overgrowth does not correspond to intestinal inflammation in cystic fibrosis. Scand. J. Clin. Lab. Invest. 70, 322–326.
  • Mądry, E., Lisowska, A., Kwiecień, J., Marciniak, R., Korzon-Burakowska, A., Drzymała-Czyż, S., Mojs, E., Walkowiak, J., 2010. Adult-type hypolactasia and lactose malabsorption in Poland. Acta Biochim. Pol. 57, 585–588.
  • Walkowiak, J., Blask-Osipa, A., Lisowska, A., Oralewska, B., Pogorzelski, A., Cichy, W., Sapiejka, E., Kowalska, M., Korzon, M., Szaflarska-Popławska, A., 2010a. Cystic fibrosis is a risk factor for celiac disease. Acta Biochim. Pol. 57, 115–118.
  • Walkowiak, J., Jankowska, I., Lisowska, A., Biczysko, M., Wierzbicka, A., Pawłowska, J., 2010. Normal levels of serum pancreatic enzymes in patients with progressive familial intrahepatic cholestasis type 2. Acta Biochim. Pol. 57, 573–575.
  • Walkowiak, J., Lisowska, A., Blask-Osipa, A., Drzymała-Czyz, S., Sobkowiak, P., Cichy, W., Breborowicz, A., Herzig, K.-H., Radzikowski, A., 2010b. Acid steatocrit determination is not helpful in cystic fibrosis patients without or with mild steatorrhea. Pediatr. Pulmonol. 45, 249–254.

 

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