Information in English

Department of Pediatric Gastroenterology and Metabolic Diseases at Poznań University of Medical Sciences – a short description.

Head: prof. Jarosław Walkowiak, MD, PhD

Address:
ul. Szpitalna 27/33
60-572 Poznań
POLAND

Telephone: +4861 8472 432 (office) / +4861 8472 339 (ward)
Fax: +4861 8472 685
E-mail: pedgastro@skp.ump.edu.pl

szpital-1-s

The ward

Ward no 13 of Karol Jonscher University Hospital provides care for children of all ages. Common causes for referral to the ward include:
- inlammatory bowel diseases
- a wide range of metabolic diseases and metabolic diseases „selective screening”
- cystic fibrosis (screening centre)
- infectious diseases of the gastrointestinal tract
- coeliac disease
- pancreatitis
- nutritional problems in surgical patients
- chronic constipation of different etiologies
- severe food allergies.

The team is experienced in enteral and parenteral nutrition.

Patients with gastrointestinal and metabolic diseases require constant psychological care which is provided both on the ward and in the ambulatory care.

The ward is a reference centre:
- for pediatric gastroenterology for the population of Great Poland voivodeship (3.4 million inhabitants)
- for pediatric metabolic diseases for the population of Great Poland and Lubusz voivodeships (4.4 million inhabitants).

Gastrointestinal tract functional investigations unit

In our functional investigations laboratory we employ 13C, hydrogen and methane breath tests, esophageal and anal manometry, 24-hour pH-metry and 24-hour esophageal pH-impedance monitoring for gastrointestinal tract diseases diagnostics.

Endoscopic investigations unit

The endoscopic investigations unit provides opportunity for examination of the upper and the lower gastrointestinal tract 24 hours a day.

DEXA

We perform dual energy X-ray absorptiometry in children and adults using a recently acquired Hologic Discovery system.

Teaching

The staff of the Department is actively involved in teaching of both Polish and foregin students of MD, nursing and dietetics programmes. Courses in pediatrics, pediatric gastroenterology, metabolic diseases and nutrition are thought. Our aim is to provide education of highest quality by teaching our students practical skills and sharing knowledge necessary for the improvement of their clinical reasoning. We value professionalism and we expect the same of our students.

Residents in pediatrics and medical interns from other hospitals in the region have the opportunity to temporarily join our team.

Members of our group teach pediatricians, general practitioners, patients and their families during conferences and meetings.

Research

Our group conducts research in cooperation with domestic and international partners. We have the expertise and the equipment necessary for nutrition research. A wide range of clinical and biochemical analyses can be performed in-house. Our main areas of interest are: nutrition, cystic fibrosis and inflammatory bowel disease.

Among our foreign partners are:

partners

 

Articles (selected)

2016

  • Walkowiak J, Glapa A, Nowak JK, Bober L, Rohovyk N, Wenska-Chyży E, Sobkowiak P, Lisowska A. Pancreatic Elastase-1 Quick Test for rapid assessment of pancreatic status in cystic fibrosis patients. J Cyst Fibros. 2016 Sep;15(5):664-8.
  • Stelmach-Mardas M, Walkowiak J. Dietary Interventions and Changes in Cardio-Metabolic Parameters in Metabolically Healthy Obese Subjects: A Systematic Review with Meta-Analysis. Nutrients. 2016 Jul 28;8(8).
  • Jonczyk-Potoczna K, Nowak JK, Madry E, Katulska K, Stezowska-Kubiak S, Moczko J, Nowicka A, Lisowska A, Walkowiak J. Secretin-enhanced Magnetic Resonance Cholangio-pancreatography in Pancreatic Insufficient and Pancreatic Sufficient Cystic Fibrosis Patients. J Gastrointestin Liver Dis. 2016 Mar;25(1):57-62.
  • Jonczyk-Potoczna K, Nowak JK, Madry E, Katulska K, Stezowska-Kubiak S, Moczko J, Lisowska A, Walkowiak J. Smaller Width of the Pancreatic Duct During Secretin-Enhanced Magnetic Resonance Cholangiopancreatography in Pancreatic-Sufficient Cystic Fibrosis Patients. Pancreas. 2016 Sep;45(8):1175-8.
  • Dziedzic K, Szwengiel A, Górecka D, Gujska E, Kaczkowska J, Drożdżyńska A, Walkowiak J. Effect of Wheat Dietary Fiber Particle Size during Digestion In Vitro on Bile Acid, Faecal Bacteria and Short-Chain Fatty Acid Content. Plant Foods Hum Nutr. 2016 Jun;71(2):151-7.
  • Drzymała-Czyż S, Jończyk-Potoczna K, Lisowska A, Stajgis M, Walkowiak J. Supplementation of ursodeoxycholic acid improves fat digestion and absorption in cystic fibrosis patients with mild liver involvement. Eur J Gastroenterol Hepatol. 2016 Jun;28(6):645-9.
  • Józefczuk J, Mądry E, Nowak J, Walkowiak M, Łochocka K, Banasiewicz T, Pławski A, Kwiecień J, Walkowiak J. Conflicting results of non-invasive methods for detection of Helicobacter pylori infection in children with celiac disease – a preliminary study. Acta Biochim Pol. 2016;63(1):1088.

2015

  • Krzyżanowska P, Pogorzelski A, Skorupa W, Moczko J, Grebowiec P, Walkowiak J. Exogenous and endogenous determinants of vitamin K status in cystic fibrosis. Sci Rep. 2015 Jul 10;5:12000.
  • Lochocka K, Bajerska J, Glapa A, Fidler-Witon E, Nowak JK, Szczapa T, Grebowiec P, Lisowska A, Walkowiak J. Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study. Sci Rep. 2015 Jul 30;5:12015.
  • Nowak JK, Jonczyk-Potoczna K, Adamczak DM, Lisowska A, Walkowiak J. Esophageal pH Monitoring in Children: A Simple Mathematical Formula for pH Probe Positioning. J Pediatr Gastroenterol Nutr. 2015 Aug;61(2):212-4.
  • Nowak JK, Grulkowski I, Karnowski K, Wojtkowski M, Walkowiak J. Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women. Clin Transl Sci. 2015 Dec;8(6):717-21.
  • Nowak JK, Grulkowski I, Karnowski K, Wojtkowski M, Walkowiak J. Optical coherence tomography identifies lower labial salivary gland surface density in cystic fibrosis. PLoS One. 2015 Jan 26;10(1):e0117517.
  • Skrypnik D, Bogdański P, Mądry E, Karolkiewicz J, Ratajczak M, Kryściak J, Pupek-Musialik D, Walkowiak J. Effects of Endurance and Endurance Strength Training on Body Composition and Physical Capacity in Women with Abdominal Obesity. Obes Facts. 2015;8(3):175-87.
  • Lisowska A, Stawińska-Witoszyńska B, Bajerska J, Krzyżanowska P, Walkowiak J. Green tea influences intestinal assimilation of lipids in humans: a pilot study. Eur Rev Med Pharmacol Sci. 2015;19(2):209-14.
  • Drzymala-Czyz S, Stawinska-Witoszynska B, Mądry E, Krzywinska-Wiewiórowska M, Szczepanik M, Walkowiak J, Kwiecien J. Non-invasive detection of Helicobacter pylori in cystic fibrosis–the fecal test vs. the urea breath test. Eur Rev Med Pharmacol Sci. 2014 Aug;18(16):2343-8.
  • Bajerska J, Mildner-Szkudlarz S, Walkowiak J. Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study. J Med Food. 2015 Jun;18(6):698-705.
  • Jozefczuk J, Bancerz B, Walkowiak M, Glapa A, Nowak J, Piescikowska J, Kwiecien J, Walkowiak J. Prevalence of Helicobacter pylori infection in pediatric celiac disease. Eur Rev Med Pharmacol Sci. 2015;19(11):2031-5.

2014

  • Czub E, Nowak JK, Moczko J, Lisowska A, Banaszkiewicz A, Banasiewicz T, Walkowiak J. Comparison of fecal pyruvate kinase isoform M2 and calprotectin in acute diarrhea in hospitalized children. Sci Rep. 4:4769. doi: 10.1038/srep04769.
  • Nowak JK, Grzybowska-Chlebowczyk U, Landowski P, Szaflarska-Poplawska A, Klincewicz B, Adamczak D, Banasiewicz T, Plawski A, Walkowiak J. Prevalence and correlates of vitamin K deficiency in children with inflammatory bowel disease. Sci Rep. 4:4768. doi: 10.1038/srep04768.
  • Grulkowski I, Nowak JK, Karnowski K, Zebryk P, Puszczewicz M, Walkowiak J, Wojtkowski M. Quantitative assessment of oral mucosa and labial minor salivary glands in patients with Sjögren’s syndrome using swept source OCT. Biomed Opt Express. 5(1): 259–274.
  • Lisowska A, Kobelska-Dubiel N, Jankowska I, Pawłowska J, Moczko J, Walkowiak J. Small intestinal bacterial overgrowth in patients with progressive familial intrahepatic cholestasis. Acta Biochim Pol. 61(1):103-7.
  • Czub E, Nowak JK, Szaflarska-Poplawska A, Grzybowska-Chlebowczyk U, Landowski P, Moczko J, Adamczak D, Mankowski P, Banasiewicz T, Plawski A, Walkowiak J. Comparison of fecal pyruvate kinase isoform M2 and calprotectin in assessment of pediatric inflammatory bowel disease severity and activity. Acta Biochim Pol. 61(1):99-102.
  • Kaluzny L, Szczepanik M, Siwinska-Mrozek Z, Borkowska-Klos M, Cichy W, Walkowiak J. Parenteral nutrition in patients with inborn errors of metabolism – a therapeutic problem. Eur Rev Med Pharmacol Sci. 18(11):1579-82.
  • Stelmach-Mardas M, Mardas M, Walkowiak J, Boeing H. Long-term weight status in regainers after weight loss by lifestyle intervention: status and challenges. Proc Nutr Soc. 2014 Nov;73(4):509-18.
  • Stelmach-Mardas M, Mardas M, Warchoł W, Jamka M, Walkowiak J. Successful maintenance of body weight reduction after individualized dietary counseling in obese subjects. Sci Rep. 2014 Oct 14;4:6620.

2013

  • Drzymała-Czyż, S., Kwiecień, J., Pogorzelski, A., Rachel, M., Banasiewicz, T., Pławski, A., Szczawińska-Popłonyk, A., Herzig, K.-H., Walkowiak, J., 2013. Prevalence of Helicobacter pylori infection in patients with cystic fibrosis. J. Cyst. Fibros.
  • Walkowiak J, Cofta S, Mozrzymas R, Siwinska-Mrozek Z, Nowak J, Kaluzny L, Banasiewicz T. Phenylketonuria is not a risk factor for gut mucosa inflammation: a preliminary observation. Eur Rev Med Pharmacol Sci. 17(22):3056-9.
  • Walkowiak J, Bajerska J, Kargulewicz A, Lisowska A, Siedlerski G, Szczapa T, Kobelska-Dubiel N, Grzymisławski M. Single dose of green tea extract decreases lipid digestion and absorption from a test meal in humans. Acta Biochim Pol. 60(3):481-3.

2012

  • Banasiewicz, T., Walkowiak, J., Drzymała-Czyż, S., Borejsza-Wysocki, M., Majewski, P., Biczysko, M., Stojcev, Z., Herzig, K.-H., Drews, M., 2012. Stricture of ileo-anal J pouch anastomosis increased the intensity of pouchitis in an experimental rat model. Med. Sci. Monit. 18, BR409–413.
  • Drzymała-Czyż, S., Banasiewicz, T., Tubacka, M., Tarasiuk-Rusek, A., Majewski, P., Drews, M., Walkowiak, J., 2012a. Discrepancy between clinical and histological effects of DHA supplementation in a rat model of pouchitis. Folia Histochem. Cytobiol. 50, 125–129.
  • Drzymała-Czyż, S., Banasiewicz, T., Walas, S., Kościński, T., Wenska-Chyży, E., Drews, M., Walkowiak, J., 2012b. Trace elements and rat pouchitis. Acta Biochim. Pol. 59, 599–601.
  • Krzyżanowska, P., Książyk, J., Kocielińska-Kłos, M., Banaś, E., Kaleta, M., Popińska, K., Szczapa, T., Walkowiak, J., 2012. Vitamin K status in patients with short bowel syndrome. Clin Nutr 31, 1015–1017.
  • Mądry, E., Krasińska, B., Drzymała-Czyż, S., Sands, D., Lisowska, A., Grebowiec, P., Minarowska, A., Oralewska, B., Mańkowski, P., Moczko, J., Walkowiak, J., 2012a. Lactose malabsorption is a risk factor for decreased bone mineral density in pancreatic insufficient cystic fibrosis patients. Eur. J. Hum. Genet. 20, 1092–1095.
  • Mądry, E., Lisowska, A., Grebowiec, P., Walkowiak, J., 2012b. The impact of vegan diet on B-12 status in healthy omnivores: five-year prospective study. Acta Sci Pol Technol Aliment 11, 209–212.
  • Walkowiak, J., Mądry, E., Lisowska, A., Szaflarska-Popławska, A., Grzymisławski, M., Stankowiak-Kulpa, H., Przysławski, J., 2012. Adaptive changes of pancreatic protease secretion to a short-term vegan diet: influence of reduced intake and modification of protein. Br. J. Nutr. 107, 272–276.

2011

  • Bajerska, J., Wozniewicz, M., Jeszka, J., Drzymala-Czyz, S., Walkowiak, J., 2011. Green tea aqueous extract reduces visceral fat and decreases protein availability in rats fed with a high-fat diet. Nutr Res 31, 157–164.
  • Drzymała-Czyż, S., Banasiewicz, T., Tubacka, M., Majewski, P., Biczysko, M., Kościński, T., Drews, M., Walkowiak, J., 2011. Inulin supplementation in rat model of pouchitis. Acta Biochim. Pol. 58, 381–384.
  • Flemström, G., Mäkelä, K., Purhonen, A.K., Sjöblom, M., Jedstedt, G., Walkowiak, J., Herzig, K.H., 2011. Apelin stimulation of duodenal bicarbonate secretion: feeding-dependent and mediated via apelin-induced release of enteric cholecystokinin. Acta Physiol (Oxf) 201, 141–150.
  • Herzig, K.-H., Purhonen, A.-K., Räsänen, K.M., Idziak, J., Juvonen, P., Phillps, R., Walkowiak, J., 2011. Fecal pancreatic elastase-1 levels in older individuals without known gastrointestinal diseases or diabetes mellitus. BMC Geriatr 11, 4.
  • Lisowska, A., Pogorzelski, A., Oracz, G., Siuda, K., Skorupa, W., Rachel, M., Cofta, S., Piorunek, T., Walkowiak, J., 2011a. Oral antibiotic therapy improves fat absorption in cystic fibrosis patients with small intestine bacterial overgrowth. J. Cyst. Fibros. 10, 418–421.
  • Lisowska, A., Pogorzelski, A., Oracz, G., Skorupa, W., Cofta, S., Szydłowski, J., Socha, J., Walkowiak, J., 2011b. Antibiotic therapy and fat digestion and absorption in cystic fibrosis. Acta Biochim. Pol. 58, 345–347.
  • Mądry, E., Fidler, E., Sobczyńska-Tomaszewska, A., Lisowska, A., Krzyżanowska, P., Pogorzelski, A., Minarowski, Ł., Oralewska, B., Mojs, E., Sapiejka, E., Marciniak, R., Sands, D., Korzon-Burakowska, A., Kwiecień, J., Walkowiak, J., 2011. Mild CFTR mutations and genetic predisposition to lactase persistence in cystic fibrosis. Eur. J. Hum. Genet. 19, 748–752.
  • Money, M.E., Walkowiak, J., Virgilio, C., Talley, N.J., 2011. Pilot study: a randomised, double blind, placebo controlled trial of pancrealipase for the treatment of postprandial irritable bowel syndrome-diarrhoea. Frontline Gastroenterol 2, 48–56.
  • Stankowiak-Kulpa, H., Krzyżanowska, P., Kozioł, L., Grzymisławski, M., Wanic-Kossowska, M., Moczko, J., Walkowiak, J., 2011. Vitamin K status in peritoneally dialyzed patients with chronic kidney disease. Acta Biochim. Pol. 58, 617–620.

2010

  • Houwen, R.H., van der Doef, H.P., Sermet, I., Munck, A., Hauser, B., Walkowiak, J., Robberecht, E., Colombo, C., Sinaasappel, M., Wilschanski, M., ESPGHAN Cystic Fibrosis Working Group, 2010. Defining DIOS and constipation in cystic fibrosis with a multicentre study on the incidence, characteristics, and treatment of DIOS. J. Pediatr. Gastroenterol. Nutr. 50, 38–42.
  • Krzyzanowska, P., Lisowska, A., Skorupa, W., Pogorzelski, A., Kamińska, B., Cichy, W., Popiel, A., Walkowiak, J., 2010. [Vitamin K deficiency in patients with CF despite supplementation]. Med Wieku Rozwoj 14, 68–72.
  • Lisowska, A., Madry, E., Pogorzelski, A., Szydłowski, J., Radzikowski, A., Walkowiak, J., 2010. Small intestine bacterial overgrowth does not correspond to intestinal inflammation in cystic fibrosis. Scand. J. Clin. Lab. Invest. 70, 322–326.
  • Mądry, E., Lisowska, A., Kwiecień, J., Marciniak, R., Korzon-Burakowska, A., Drzymała-Czyż, S., Mojs, E., Walkowiak, J., 2010. Adult-type hypolactasia and lactose malabsorption in Poland. Acta Biochim. Pol. 57, 585–588.
  • Walkowiak, J., Blask-Osipa, A., Lisowska, A., Oralewska, B., Pogorzelski, A., Cichy, W., Sapiejka, E., Kowalska, M., Korzon, M., Szaflarska-Popławska, A., 2010a. Cystic fibrosis is a risk factor for celiac disease. Acta Biochim. Pol. 57, 115–118.
  • Walkowiak, J., Jankowska, I., Lisowska, A., Biczysko, M., Wierzbicka, A., Pawłowska, J., 2010. Normal levels of serum pancreatic enzymes in patients with progressive familial intrahepatic cholestasis type 2. Acta Biochim. Pol. 57, 573–575.
  • Walkowiak, J., Lisowska, A., Blask-Osipa, A., Drzymała-Czyz, S., Sobkowiak, P., Cichy, W., Breborowicz, A., Herzig, K.-H., Radzikowski, A., 2010b. Acid steatocrit determination is not helpful in cystic fibrosis patients without or with mild steatorrhea. Pediatr. Pulmonol. 45, 249–254.

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